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§ 05 — CONDITION DEEP DIVE

SUBSTANCE USE

Cannabis use disorder is real. Tolerance, dependence, and withdrawal are real. This section is for veterans who want to understand the risks — and for those who want help.

What Veterans Report

Some veterans report that cannabis has been a positive force in their lives — replacing alcohol, reducing opioid use, or providing relief that other treatments did not. These experiences are real and valid.

Other veterans report that cannabis became a problem. They developed tolerance, needed more for the same effect, and struggled to stop. Some experienced withdrawal — insomnia, irritability, anxiety, loss of appetite. These experiences are equally real and valid.

What Observational Research Shows

Approximately 2.5% of U.S. adults meet criteria for cannabis use disorder (CUD) in a given year. Prevalence is higher among individuals with co-occurring mental health conditions, including veterans with PTSD. CUD involves problematic use that causes significant impairment or distress.

What Randomized Trials Show

Research on cannabis use disorder treatment is limited. No medication is FDA-approved for CUD. Evidence-based treatments include cognitive behavioral therapy (CBT) and motivational enhancement therapy (MET). The VA offers treatment for substance use disorders, including CUD.

What Systematic Reviews Say

Systematic reviews have confirmed that cannabis can produce tolerance, dependence, and withdrawal. Cannabis withdrawal syndrome is recognized in the DSM-5. Symptoms include irritability, anxiety, sleep difficulty, decreased appetite, and physical discomfort.

What the VA Says

The VA offers treatment for substance use disorders, including cannabis use disorder. Veterans can ask their VA provider for help. Treatment options include therapy, support groups, and in some cases medication for co-occurring conditions.

The SAMHSA National Helpline (1-800-662-4357) provides free, confidential, 24/7 treatment referral and information.

Known Risks

Regular cannabis use can lead to tolerance (needing more for the same effect), dependence (experiencing withdrawal without it), and cannabis use disorder (problematic use despite negative consequences). These risks increase with frequency of use, potency of products, and younger age of first use.

Cannabis withdrawal is real and can be uncomfortable. Symptoms typically begin within 1-3 days of stopping, peak in the first week, and resolve within 1-2 weeks. Sleep disturbance can persist longer.

What Remains Unknown

We do not fully understand which individuals are most at risk for developing CUD. We do not know how product potency (THC percentage) affects CUD risk. We do not have highly effective treatments for CUD.

Questions to Ask Your Healthcare Provider

• How can I tell if my cannabis use is becoming a problem? • What treatment options are available through the VA for cannabis use disorder? • What should I expect if I stop using cannabis? • Are there support groups for veterans who want to reduce or stop cannabis use? • How can I talk to my family about my cannabis use?

Sources

SOURCES & VERIFICATION

Hasin et al. (2016) American Journal of Psychiatry; DSM-5 cannabis withdrawal criteria; VA substance use treatment; SAMHSA National Helpline

LAST VERIFIED: SEPTEMBER 2026 · ALL SOURCES CHECKED AGAINST ORIGINAL PUBLICATIONS

DISCLAIMER

This page is educational and does not provide medical diagnosis, treatment, or individualized healthcare recommendations. Cannabis affects people differently and carries risks. Always discuss medical decisions, medication changes, and cannabis use with a qualified healthcare professional. Cannabis laws vary by jurisdiction and change over time. Always confirm current law through official government sources.

RELATED RESEARCH

Studies in the research library

SYSTEMATIC REVIEW · 2023

Cannabis and Symptoms of PTSD: A Systematic Review

Mixed evidence. Some studies suggest cannabis may reduce PTSD symptoms in the short term; others find cannabis use associated with worse PTSD outcomes long-term. Evidence insufficient for clinical recommendation.

META ANALYSIS · 2017

Cannabis Use and Anxiety: A Meta-Analysis

Cannabis use associated with increased odds of anxiety and depressive symptoms. Causality cannot be established — cannabis may be used to self-medicate symptoms.

CROSS SECTIONAL STUDY · 2017

Cannabis Use in Older Adults: Trends and Health Implications

Cannabis use among adults 50+ increased significantly. Older adults face elevated risks from drug interactions, falls, and cognitive effects.

SYSTEMATIC REVIEW · 2017

The Health Effects of Cannabis and Cannabinoids: The Current State of Evidence and Recommendations for Research

Substantial evidence that cannabis/cannabinoids reduce chronic pain in adults. Moderate evidence for improved sleep in chronic pain patients. Limited evidence for PTSD treatment.

§ 13 — CRISIS & SUPPORT RESOURCES

IF YOU ARE IN CRISIS, HELP IS AVAILABLE NOW.

Cannabis is not a crisis treatment. If you are struggling, please reach out to the resources below. These services are free, confidential, and available 24/7.

Veterans Crisis Line

Dial 988, then press 1. Or text 838255.

VETERANSCRISISLINE.NET

VA Mental Health

VA offers mental health services for veterans. Contact your VA medical center or call 1-800-273-8255.

MENTALHEALTH.VA.GOV

SAMHSA Helpline

Free, confidential treatment referral. Call 1-800-662-4357. Available 24/7 in English and Spanish.

SAMHSA.GOV

CONTACT INFORMATION VERIFIED AGAINST OFFICIAL SOURCES. ALWAYS CONFIRM CURRENT NUMBERS DIRECTLY. CANNABIS IS NOT PRESENTED AS A CRISIS TREATMENT.